Proteins are large, complex molecules that carry out the tasks of life. They direct our bodies' activities, organize our thoughts, and defend us against infection, keeping us healthy. But in their ...
Just like workers need the right environment to efficiently perform their tasks, proteins require placement within specific cellular compartments to function properly. Therefore, understanding the ...
Historically, these factors have made the identification of proteins incredibly challenging. The advent of mass spectrometry (MS) and MS-based proteomics helped to change that. 2 MS is an analytical ...
This episode of the Pharmaron DMPK Insights Podcast Series features Scott Summerfield (Executive Director of Metabolism at Pharmaron) and John Mehl (consultant and previous director at GSK, and ...
A screening technique commonly used in drug discovery can yield important details about the actions of molecular ‘glues’ in protein interactions. Molecular glues are emerging as powerful therapeutic ...
As our bodies run multiple parallel processes, they shuttle a flurry of messages around inside—often as protein-metabolite interactions (PMIs), where small molecules bind to a protein and initiate or ...
A new prototype could supercharge mass spectrometry by analyzing thousands of molecules at once instead of one by one. The ...
Hydrogen/deuterium exchange coupled to mass spectrometry (HX-MS) is a valuable technique for analyzing the structural features and dynamic properties of individual proteins and large protein complexes ...
New Jersey Institute of Technology (NJIT) researchers have unveiled a new lab technique they say represents a "paradigm shift" in how pharmaceutical laboratories test and produce new protein-based ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results