Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...

Scientists reveal a hidden second layer of human DNA, showing how genome folding controls genes and influences disease development.

The MCM helicase is broadly bound across the genome, and its phosphorylation is antagonistically regulated by the kinase DDK and the phosphatase RIF1–PP1. TRESLIN–MTBP recognises the phosphorylated ...

Patients with this genetic disorder have a form of dwarfism — they are short in stature and have underdeveloped ears and ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

CDCA7, whose mutations alter DNA methylation pattern and cause immunodeficiency, is a novel sensor for a special class of methylated DNA. DNA methylation is a process in which a methyl group is ...

Most of the cells in our body carry the genome, and those cells are constantly bombarded with environmental influences including UV rays, pollution, alcohol, and other exposures that can damage the ...

Tampa (BLOOM) – Understanding the intricate process of aging has been a subject of fascination for scientists and researchers. While aging is a natural part of life, recent studies have shed light on ...